Web30 Jan 2024 · Resolution of ultrafine anaphase bridges (UFBs) must be completed before cytokinesis to ensure sister-chromatid disjunction. RIF1 is involved in UFB resolution by a … Web12 Mar 2015 · Here, the authors report that topoisomerase IIβ binding protein 1 recruits topoisomerase IIα to centromere-associated ultra-fine anaphase bridges to enable their …
Detection of Ultrafine Anaphase Bridges SpringerLink
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BLM is required for faithful chromosome segregation and its ...
Web25 Sep 2024 · Ultrafine anaphase bridges (UFBs) are a potential source of genome instability that is a hallmark of cancer. UFBs can arise from DNA catenanes at … WebEventually, in mitosis, they can evolve into ultrafine anaphase bridges (UFBs) connecting sister chromatids, which can finally lead to chromosomal instability. In the following sections, we focus on CFSs as an example of the extraordinary processes that cells carry out in mitosis to resolve problems that originated during the previous S-phase, in order to … Web1 Jun 2024 · Although chromatin bridges and lagging chromatin are always pathological (generating aneuploidy or complex genomic rearrangements), the main subject of this article, the ultrafine anaphase bridges, might, in addition to potentially driving genomic instability, play critical roles for the maintenance of chromosome structure in rapidly ... edge insecurecontentallowedforurls