Phospholipase a2 gene
WebHas phospholipase A2 activity toward platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine), likely playing a role in inactivation of this potent pro-inflammatory signaling lipid ( By similarity ). In response to glucose, amplifies calcium influx in pancreatic beta cells to promote INS secretion ( By similarity ). WebMar 28, 2024 · In a Serbian brother and sister with GURDP, Brooke et al. (2014) identified a homozygous 4-bp deletion in the PLA2G4A gene ( 600522.0004 ). The mutation, which …
Phospholipase a2 gene
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WebNov 15, 1991 · Phospholipase A 2 (PLA 2) participates in a wide range of cellular processes including inflammation and transmembrane signaling. A human nonpancreatic secretory PLA 2 (hnps-PLA 2) has been identified that is found in high concentrations in the synovial fluid of patients with rheumatoid arthritis and in the plasma of patients with septic shock. WebDec 1, 2024 · Phospholipase A2 (PLA2), a phospholipid hydrolase, has recently attracted attention owing to its broad functionality. Immunological evidence has revealed increased …
WebPhospholipase A2 Gene PLA2G1B Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 148 Protein existence Evidence at protein level Annotation … WebSullivan CP, Seidl SE, Rich CB et al Secretory phospholipase A2, group IIA is a novel serum amyloid A target gene: activation of smooth muscle cell expression by an interleukin-1 receptor-independent mechanism. J Biol Chem 285:565–575
WebPhospholipase A2. Phospholipase A2 (PLA2) is one of a family of phospholipases, enzymes that hydrolyse phospholipids. From: Clinical Biochemistry: Metabolic and Clinical Aspects … WebCalf skeletal muscle gene expression of patients with PAD and healthy subjects was analyzed using microarrays. The top-ranking gene differentially expressed between PAD and controls (FDR < 0.001) was PLA2G16 , which encodes adipose-specific phospholipase A2 (AdPLA) and is implicated in the maintenance of insulin sensitivity and regulation of ...
WebPLA2 provides precursors for generation of eicosanoids, such as prostaglandins (PGs) and leukotrienes (LTs), when the cleaved fatty acid is arachidonic acid, platelet-activating factor (PAF) when the sn-1 position of the phosphatidylcholine contains an alkyl ether linkage and some bioactive lysophospholipids, such as lysophosphatidic acid (lysoPA).
WebBackground Ureases are multifunctional enzymes that display biological activities independent of their enzymatic function, including exocytosis induction and insecticidal effects. The hemipteran Rhod how much of keto weight loss is waterWebApr 3, 2024 · Phospholipase A2 Group IIa may be a modifier gene for fundic gland polyposis in patients with familial adenomatous polyposis PLA2G2A haplotypic variation strongly … how do i title a spreadsheetWebENCODES a protein that exhibits calcium-independent phospholipase A2 activity (ortholog); lysophospholipase activity (ortholog); O-acyltransferase activity (ortholog); INVOLVED IN … how much of kitchen nightmares is stagedWebMar 28, 2024 · PLA2B, the synovial phospholipase A2 described by Seilhamer et al. (1989), is a small molecular weight enzyme that is DTT-sensitive. PLA2B is secreted from cells, active in the micromolar to millimolar calcium concentration range that prevails in the extracellular medium, and active in inflammatory exudates. how much of keystone xl was builtWebNov 16, 2015 · Astrocytic phospholipase A2 contributes to neuronal glutamate toxicity.pdf 2015-11-16 上传 Astrocytic phospholipase A2 contributes to neuronal glutamate toxicity how much of keystone xl was completedWebSpecifically, the A2 phospholipase produced from the PLA2G6 gene, sometimes called PLA2 group VI, helps to regulate the levels of a compound called phosphatidylcholine, which is … how much of keystone pipeline oil is exportedWebBackground Ureases are multifunctional enzymes that display biological activities independent of their enzymatic function, including exocytosis induction and insecticidal … how do i toast coconut