Web13 jul. 2024 · Mitomycin (MMC) has been frequently used as the compound for intravesical treatment. The relatively new pyrimidine analog gemcitabine (GEM) has … WebHowever, as was shown in this meta-analysis, intravesical Gem might have similar efficacy to BCG. In addition to efficacy, clinicians also pay attention to adverse effects. This meta-analysis showed that intravesical Gem might have lower incidence of dysuria and hematuria, indicating that it may offer good side effect profile for clinical use.
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WebSo far, few case reports dealing with complications using mitomycin C have been published, but severe complications of leakage after an early adjuvant instillation with epirubicin have not been reported. Methods: We describe 3 patients in whom we observed serious complications of one immediate postoperative instillation of epirubicin. WebThe treatment involves instillations of liquid chemotherapy (mitomycin C) into the bladder through a catheter once a week for six weeks. This is recommended for intermediate risk (potentially aggressive, multiple or recurrent tumour) superficial cancer of the bladder. Superficial bladder cancer has the potential to recur. in what organelle does replication take place
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WebAdverse Effects >10% Hemolytic uremic syndrome (≤15%) Myelosuppression (64%) Nausea/vomiting (14%) Fever (14%) 1-10% Stomatitis (4%) Increased serum creatinine (2%) Mucous membrane toxicity (4%)... Web1 nov. 2024 · Epirubicin, gemcitabine, and pirarubicin are widely used as first-line drugs for intravesical chemotherapy to prevent tumor recurrence after transurethral bladder tumor resection for non-muscle-invasive bladder cancer (NMIBC). However, which drug is better is less discussed. A total of 335 NMIBC patients administered intravesical chemotherapy … Web2 feb. 2024 · Intravesical Mitomycin C, Epirubicin, and Gemcitabine are cytotoxic agents that inhibit DNA synthesis in bladder cancer cells. ... Side Effects Not Requiring … in what organelle is dna found