Web1 jan. 2013 · In humans, mDC are defined as CD11c + CD123 low whereas pDC are CD11c − CD123 high. In mice, both mDC and pDC are CD11c-positive. However, mouse mDC are CD11c high CD11b high B220 − whereas mouse pDC are CD11c low CD11b − B220 +. As a consequence, cell surface CD11c is commonly used as a mouse DC marker. WebThe myeloid DCs (mDC) are derived from the common myeloid progenitor (CMP) that also gives rise to macrophages, while the plasmacytoid DCs (pDC) are derived from the common lymphoid progenitor (CLP) that also gives rise to B cells, T cells, and NK cells. From: Scientific Principles of Adipose Stem Cells, 2024 View all Topics Add to Mendeley
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