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WitrynaIndications and Dosage. Adult: As loperamide hydrochloride cap: Initially, 4 mg daily; adjusted until 1-2 solid stools a day are obtained, which is usually achieved with maintenance dose of 2-12 mg daily. Max: 16 mg daily. As loperamide hydrochloride oral solution: Initially, 4-8 mg daily in divided doses, may be adjusted depending on … WitrynaRuben Vardanyan, in Piperidine-Based Drug Discovery, 2024. Loperamide (3756) Loperamide (5.2.35) (Imodium) is a peripherally acting μ-opioid receptor agonist and an avid substrate for P-glycoprotein.It is an over-the-counter medication that is used for the relief of diarrheal syndromes, including acute, nonspecific (infectious) diarrhea; … Witryna23 maj 2024 · Mechanism of Action. Loperamide is a highly lipophilic synthetic phenylpiperidine opioid. Loperamide is a mu- receptor … phoenix ong cleaning service ipoh