WebJan 11, 2024 · An endophytic fungus, Alternaria alternata was isolated from Grewia asiatica.Upscaling of the fermentation broth led to the isolation of a new structural isomer of alternariol (3), along with alternariol (1) and alternariol 9-methyl ether (2).Additionally, an LC-ESI-MS/MS method was developed for the simultaneous detection and quantification … WebJun 1, 2001 · In this study, the possible toxic effects of Alternariol Methyl Ether (AME) and Tenuazonic Acid (TeA) produced by Alternaria species on esophagus of mice were investigated by using light and electr...
(PDF) Analysis of Toxic Effects of Alternaria Toxins …
WebThe filamentous fungus Alternaria alternata is a potent producer of many toxic secondary metabolites, which contaminate food and feed. The most prominent one is the polyketide-derived alternariol (AOH) and its derivative alternariol monomethyl ether (AME). Here, we identified the gene cluster for the biosynthesis of AOH and AME by CRISPR/Cas9 ... WebFeb 1, 2024 · Humans are typically exposed to mixtures of substances, whereby their bioactivity can be significantly altered by co-occurring compounds. Thus, over the last years, research on combinatory effects has gained increasing attention. ... Combinatory estrogenic effects of bisphenol A in mixtures with alternariol and zearalenone in human … crfxfnm csuyfk
Cytotoxicities of Co-occurring alternariol, alternariol …
WebJan 14, 2015 · Abstract. A total of 70 tomato-based and 86 citrus-based products collected in China were analyzed for alternariol, alternariol monomethyl ether, tentoxin, and tenuazonic acid by ultraperformance liquid chromatography–electrospray ionization–tandem mass spectrometry. No toxins were found in any fresh tomato or citrus fruit samples. Weband alternariol may be factors in human oesophageal cancer (An et al., 1989; Liu et al., 1992). 3 Occurrence of these toxins has been observed in a few raw and processed commercial products including cereal grains, oils, grapes, tomatoes, and apples (EFSA, 2011). Some assessments have WebDeoxynivalenol (DON) and emerging Alternaria toxins often co-occur in cereal-based products, but the current risk assessment is commonly conducted for only one type of mycotoxin at a time. Compared to adults, infants and young children are more susceptible to mycotoxins through food consumption, especially with cereal-based food products which … buddy holly wife today